Historically, in all cultures, herbs were employed for overall health and immune balance. In modern times, scientific research often discovers the efficacy of plant nutrients and molecules, confirming thousands of years of beneficial uses. One very popular herb is goldenseal. Historically it was used as a digestive bitter, and as immune system support. Scientific research confirms that goldenseal has both digestive- and immune-supportive properties thought to be from its inherent alkaloid: berberine and canadine.