B-Replete is an advanced B-complex providing the entire spectrum of B vitamins and other complementary nutrients to support healthy homocysteine metabolism, adrenal, energy and neurological function as well as healthy stress response. B-Replete provides activated forms of vitamins B2, B6 and B12, with the addition of benfotiamine, a fat soluble and physiologically active form of thiamin. The 5-MTHF in this formula – Quatrefolic – is the most biologically active form of folate, allowing rapid uptake into the bloodstream. The 5-MTHF in this formula is also known as the "L" form of 5-MTHF since it is the reduced form of folate. The addition of PABA, vitamin C and therapeutic doses of B12 and B6 make this a powerful and comprehensive activated B-complex that stands out above the rest.