• Promotes an Overall Sense of Calm
• Helps Promote Relaxation & Reduced Nervousness
• Maintains Healthy Neurotransmitter Release (Specifically, GABA)
• Promotes Both Healthy REM & Non-REM Sleep Cycles

Active Ingredient: DHH-B (Dihydrohonokiol-B)

Other Ingredients: Cellulose, Rice Powder, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose, Titanium Dioxide)

DHH-B exerts its biological effects through multiple mechanisms, contributing to its diverse pharmacological activities. One of its primary mechanisms of action is through GABAergic modulation. It acts as a positive allosteric modulator of gamma-aminobutyric acid (GABA) receptors, enhancing GABAergic neurotransmission.

In addition to its GABAergic effects, DHH-B also influences the release and reuptake of various other neurotransmitters, including dopamine, serotonin, and norepinephrine. By promoting levels of these neurotransmitters, DHH-B exhibits potential support for mood, relaxation, and coganative function.

Another important aspect of DHH-B is its ability to support the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukins (IL-1β, IL-6).

Furthermore, DHH-B displays robust antioxidant properties. It is a scavenger of reactive oxygen species (ROS) and upregulates endogenous antioxidant enzymes. These antioxidant effects contribute to its neuroprotective and anti-aging properties. DHH-B’s antioxidant and neuroprotective properties make it a candidate for supporting neurologic physiology and functionality to promote both short term and long term brain health.

The compound's potential to provide inflammatory support suggests its possible application use in helping to maintain healthy joints and well functioning digestive and immune systems.